Popular culture has become increasingly saturated with information about and strategies purported to enhance brain and cognitive health. But what does the science say? What’s hype, and what actually works? In this course, we will provide background information about the brain and how it functions, consider prevalent beliefs about the brain that may or may not be accurate, and provide an overview of factors associated with promoting cognitive health across the lifespan. We will review lifestyle activities that have been found to promote cognitive health, and discuss lifestyle changes and self-coaching strategies that may reduce the likelihood of cognitive problems. Notable psychological, neuropsychological, and neuroimaging studies will be incorporated as they relate to course topics. The course will involve a combination of lecture, class participation, reading assignments, and participant exercises.